Children’s National Hospital becomes first pediatric hospital designated a Center of Excellence by Focused Ultrasound Foundation

September 24, 2020

Extra precise, fewer invasive and fewer agonizing surgical procedure with decreased threat of difficulties and no radiation exposure – these are some of the benefits of managing pediatric tumors with Magnetic Resonance Guided Large Depth Centered Ultrasound (MR-HIFU). And now the Centered Ultrasound Basis has specified Children’s Nationwide Healthcare facility as the 1st international pediatric Heart of Excellence (COE) for employing this technologies to support people with precise forms of childhood tumors. 

“This designation delivers a higher amount of recognition and legitimacy to the get the job done our Children’s Nationwide group has carried out with MR-HIFU over many yrs,” suggests Karun Sharma, M.D., Ph.D, director of Interventional Radiology and affiliate director of medical translation at the Sheikh Zayed Institute for Pediatric Surgical Innovation (SZI) at Children’s Nationwide. “This will permit our focused ultrasound plan to grow to other parts of curiosity and come to be a lot more cohesive whilst continuing to uncover additional medical indications for pediatric people.”

At Children’s Nationwide, radiologists use MR-HIFU to aim an ultrasound beam into lesions, usually tumors of the bone and tender tissues, to heat and destroy the tissue in that region. There are no incisions at all. In 2015, Children’s Nationwide medical doctors became the 1st in the U.S. to use MR-HIFU to treat pediatric osteioid osteoma, a agonizing, but benign, bone tumor that commonly takes place in little ones and youthful older people. The demo, led by Dr. Sharma, shown early achievement in setting up the security and feasibility of noninvasive MR-HIFU in little ones as an alternate to the recent, a lot more invasive techniques to treat these tumors.  The group also done a further medical demo, led by AeRang Kim, M.D., Ph.D, a pediatric oncologist, to treat relapsed tender tissue tumors these kinds of as sarcomas.   

Considering that then, the Children’s Nationwide group has crafted an energetic medical trials plan and come to be a chief in translation of focused ultrasound for the cure of pediatric sound tumors. The centre is currently investigating the cure of malignant sound tumors with focused ultrasound by yourself and blended with chemotherapy.

“Focused ultrasound delivers a range of vital benefits over regular therapies, which are specially paramount for the pediatric populace,” said Centered Ultrasound Basis Chairman Neal F. Kassell, M.D. “The group at Children’s Nationwide has an exemplary monitor record in employing this technologies to pioneer new cure alternatives for their people, and we appear ahead to collaborating and supporting their long term investigate.”

As a specified COE, Children’s Nationwide has the necessary infrastructure to support the ongoing use of this technologies, specially for carrying out long term pediatric medical trials. This infrastructure involves an ethics committee common with focused ultrasound, a robust medical trials investigate support group, a facts critique committee for ongoing security checking and annual security opinions, and a scientific critique committee for protocol analysis.

The plan also options a multidisciplinary group of clinicians and investigators from SZI, radiology, oncology, surgical procedure and orthopedics. With the new designation and ongoing enlargement, we will grow MR-HIFU to other parts these kinds of as neuro-oncology, neurosurgery, and urology. Ongoing and long term get the job done will look into a rational blend of MR-HIFU with local tumor drug supply, immunotherapy and mobile therapy. 

“This recognition sets us aside as a leading pediatric institution, and will permit us to pave the way to make pediatric surgical procedure a lot more precise and fewer invasive,” suggests Dr. Sharma.

Media speak to: Gabrielle Little | 860-818-2345

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