Children’s National Hospital becomes part of the national CAUSE Clinical Research Network under a $3 million grant


The Countrywide Institute of Allergy and Infectious Disorders grant will assistance the consortia to additional strengthen asthma interventions and preventions


April 26, 2021

The Countrywide Institute of Allergy and Infectious Disorders (NIAID) allocated $10 million in funding to build the Childhood Bronchial asthma in the City Setting (Lead to) community. The NIAID programs to enhance this variety by $70 million above seven several years to assistance the community. Children’s Countrywide Hospital will be component of the new investigation community, which is a seven-12 months consortium comprised of seven scientific internet sites in six different cities that will be a part of forces to carry out mechanistic and translational reports inspecting the basic immunology of pediatric asthma among the city, underneath-resourced and largely minority small children and adolescents. 

Children’s Countrywide is the household of Bettering Pediatric Bronchial asthma Treatment in the District of Colombia (Impression DC). The system focuses on investigation, care, and advocacy to reduce asthma morbidity expert by at-possibility youth in the area even though serving as a model system for the country. NIAID gave an initial $3 million to Impression DC to perform its have pilot study of anti-IgE treatment to reduce asthma exacerbations. More assistance for this and other reports will come from subcontracts from the Lead to Coordinating Center at the University of Wisconsin in Madison.

“This new award allows Impression DC to remain component of one of the nation’s most prestigious pediatric asthma investigation consortia,” said Stephen Teach, M.D, M.P.H., chair for the Section of Pediatrics at George Washington University College of Drugs and Overall health Sciences. “It will enable us to the two pursue an unbiased investigation agenda even though collaborating with identical academic facilities nationwide.”

Pediatric asthma is the most frequent long-term ailment in small children, and it is believed that about 6.one million small children underneath eighteen several years endure from this affliction. It disproportionately has an effect on city, minority and underneath-resourced small children and adolescents.

“It is crucial to produce an comprehension of the basic immunology of the ailment and therapeutic solutions to ameliorating these disparities,” said Dr. Teach.

Lead to researchers will take a look at the mechanisms of immune tolerance to allergens, the role of early environmental exposures in the pathogenesis of asthma, the pathogenesis and mechanisms of non-atopic asthma, the role of the respiratory epithelium in asthma and extra.

The Lead to community comprises seven scientific investigation facilities, together with Children’s Countrywide led by principal investigator, Dr. Teach, and the adhering to investigation facilities:

  • Boston Children’s Hospital. Principal investigators: Wanda Phipatanakul, M.D. and Talal Chatila, M.D.
  • Cincinnati Children’s Hospital Medical Center. Principal investigator: Gurjit Khurana Hershey, M.D., Ph.D. 
  • Columbia University Overall health Sciences, New York. Principal investigator: Meyer Kattan, M.D. 
  • Icahn College of Drugs at Mount Sinai, New York. Principal investigators: Paula Busse, M.D. Supinda Bunyavanich, M.D. and Juan Wisnivesky, M.D. 
  • Lurie Children’s Hospital of Chicago. Principal investigators: Rajesh Kumar, M.D. and Jacqueline Pongracic, M.D. 
  • University of Colorado Denver. Principal investigator: Andrew Liu, M.D. 

Media contact: Valeria Sabate


About Children’s Countrywide Hospital

Children’s Countrywide Hospital, primarily based in Washington, D.C., celebrates 150 several years of pediatric care, investigation and motivation to community. Volunteers opened the clinic in 1870 with twelve beds for small children displaced soon after the Civil War. Today, 150 several years much better, it is among the the nation’s best 10 children’s hospitals. It is ranked No.one for new child care for the fourth straight 12 months and ranked in all specialties evaluated by U.S. Information & Globe Report. Children’s Countrywide is reworking pediatric drugs for all small children. In 2021, the Children’s Countrywide Exploration & Innovation Campus will open, the first in the country devoted to pediatric investigation. Children’s Countrywide has been specified 3 instances in a row as a Magnet® clinic, demonstrating the maximum criteria of nursing and individual care shipping and delivery. This pediatric academic wellbeing process delivers qualified care by means of a practical, community-primarily based major care network and specialty care locations in the D.C. metropolitan region, together with the Maryland and Northern Virginia suburbs. Children’s Countrywide is household to the Children’s Countrywide Exploration Institute and Sheikh Zayed Institute for Pediatric Surgical Innovation and is the nation’s seventh-maximum NIH-funded children’s clinic. It is acknowledged for its knowledge and innovation in pediatric care and as a robust voice for small children by means of advocacy at the nearby, regional and countrywide degrees.

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